Talk:Factor XII

Physiology Mid‑importance

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Molecular Biology: MCB

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Untitled[edit]

Can someone please change this sentence in the deficiency section. "Deficiency does not cause excessive hemorrhage as the other coagulation factors make up for the it". Do I even need to explain?

Deficiency[edit]

I changed the Deficiency section to reflect factor XIIa's apparent lack of involvement in thrombin formation.

Rileypaulw (talk) 22:33, 7 January 2009 (UTC) rileypaulw —Preceding unsigned comment added by Rileypaulw (talk • contribs) 22:20, 7 January 2009 (UTC)[reply]

Suggested change to diagram: surely the important part of the activation of factor XII is polyphosphates from platelets, not " damaged surface " http://www3.interscience.wiley.com/journal/117993487/home Journal of Haemostasis and Thrombosis April 2010 —Preceding unsigned comment added by Hreid11 (talk • contribs) 03:45, 23 May 2010 (UTC)[reply]

Heart disease[edit]

Another indication that we've been all wrong about factor XII for decades. The lower the FXII activity, the higher the risk for coronary heart disease doi:10.1111/j.1538-7836.2007.02839.x JFW | T@lk 21:22, 22 November 2007 (UTC)[reply]

Redirection from YII[edit]

Search word yii redirects to this article. I think it should not be so Ssavilam (talk) 07:09, 5 June 2010 (UTC)[reply]

link to multiples sclerosis found[edit]

There were found links to FXII and multiples sclerosis wouldnt it be interesting in the wiki article ? Can someone maybe research this with a little more background knowledge ? It would also be interesting to know which substances influence that factor. like infestine-4 — Preceding unsigned comment added by 87.191.19.138 (talk) 16:37, 6 September 2016 (UTC)[reply]

Review[edit]

Review in Blood about the physiological function of F XII and potential therapeutic implications. doi:10.1182/blood-2012-07-292094 JFW | T@lk 22:41, 25 November 2012 (UTC)[reply]

Another review discussing the exact function of FXII doi:10.1111/jth.13383 JFW | T@lk 13:11, 20 June 2016 (UTC)[reply]