File:CLC-5 Mutations.jpg

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Description Three-dimensional homology model of human CLC-5 based on the structure of ClC-ec1 (7) showing the locations of each mutated residue. Mutations are color coded according to their class; class 1 (red), class 2 (blue), and class 3 (green) and are shown with side chains in space fill. Views of the CLC-5 dimer observed from the side (A) demonstrate the location of all mutations near the subunit interface. Views from the extracellular face (B) and of the subunit interface (C) demonstrate a clear distinction in the distributions of each class of mutations. Only a single subunit is shown in B and C for clarity.
Author or
copyright owner
American Journal of Physiology
Source (WP:NFCC#4) http://ajprenal.physiology.org/content/296/2/F390/F6.expansion
Date of publication n/a
Use in article (WP:NFCC#7) Dent's disease
Purpose of use in article (WP:NFCC#8) The mutation of the CLC-5 gene responsible for Dent's Disease
Not replaceable with
free media because
(WP:NFCC#1)
n.a.
Minimal use (WP:NFCC#3) The article is not reproducing the entire power point teaching slide of this topic, rather the model of the genetic mutation is being used in the article for educational purposes.
Respect for
commercial opportunities
(WP:NFCC#2)
n.a.
Fair useFair use of copyrighted material in the context of Dent's disease//en.wikipedia.org/wiki/File:CLC-5_Mutations.jpgtrue

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Date/TimeThumbnailDimensionsUserComment
current13:51, 7 January 2017Thumbnail for version as of 13:51, 7 January 2017302 × 330 (21 KB)DatBot (talk | contribs)Reduce size of non-free image (BOT - disable)
15:46, 13 July 2012No thumbnail1,168 × 1,280 (256 KB)Virgil Vaduva (talk | contribs)Uploading an excerpt from a non-free work using File Upload Wizard
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